The St. Louis Cardinals (54-48) lost to the Chicago Cubs (42-58) on Sunday afternoon in ten innings by a score of 4-2. In the bottom of the tenth inning, Anthony Rizzo hit a two-run walk-off home run off Trevor Rosenthal (0-1) to give the Cubs the game and the series.

The Cubs took an early lead of 2-0 after scoring once in the first two innings, but it was shortly thereafter that Adam Wainwright settled down and gave the Cardinals yet another quality outing, allowing two earned runs on six hits over six innings pitched, while throwing 88 pitches.

Paul Maholm, who came into the game with a 0.94 ERA since June 29, was dominant,  allowing one run and four hits over 6 2/3 innings pitched. It was only in the seventh inning where trouble seemed to appear for Maholm after Tyler Greene hit a sacrifice fly allowing David Freese to score. With the bases loaded, Cubs manager Dale Sveum replaced Maholm with reliever Manuel Corpas who subsequently retired Allen Craig on a fly ball to right field.

In the eighth, Carlos Beltran, batting left-handed, took advantage of the small confines of Wrigley field, knocking an opposite-field home run to tie the game at 2-2. In the bottom of the inning, Mitchell Boggs came into the game and threw another two scoreless innings, extending his streak to 18 appearances in which he has not allowed a run.

Unfortunately, though, the Cardinals could not prevail as rookie Trevor Rosenthal let up the game-winning home run in the bottom of the tenth inning to Anthony Rizzo, his seventh of the year.

Obviously this was a frustrating loss. With it seeming like the Cincinnati Reds will never lose again, these are the types of games that are really tough to swallow, particularly when you come back late in the game just to lose it. For what it’s worth, I thought something very notable in this game was the Cards’ defense. While Daniel Descalco‘s error in the second inning resulted in another Cub run, Descalso made two fantastic plays on ground balls to rob a couple base hits which could have been trouble for the Cards. And in the sixth and seventh innings, Yadier Molina proved why he has the reputation of being one of the best defensive catchers in the game by throwing out Anthony Rizzo and Darwin Barney, respectively, to end the inning.

You’re not going to win every game, and you’re not going to win every series. Yes, today was definitely a game the Cards could have won with a little better execution with runners in scoring position (0-for-4 with 10 runners left on base), but I’m looking forward to seeing this team head to Colorado and to take advantage of another friendly hitting ballpark in Coors Field.

What’s Next: The Cardinals have the day off on Monday and then travel to Coors Field to take on the Colorado Rockies, where Kyle Lohse (10-2, 2.71) will take on Jeff Francis (3-2, 4.97) in the first of a three-game set. Game time will be 7:40 CST and can be seen on Fox Sports Midwest.